Text Box: Chen group 
陈以昀课题组
Text Box: State Key Laboratory of Bioorganic and Natural Products Chemistry
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
中国科学院上海有机化学研究所生命有机化学国家重点实验室

publications

31. Illuminating Biology with Visible-Light-Induced Biocompatible Reactions.  PDF

Chen, Y.* Chemphotochem. 2020, 4, 319-320. Meet the board.

 

30. Visible-Light-Induced Alkoxyl Radicals Enable α-C(sp3)-H Bond Allylation.  PDF

Zhang, J.1; Liu, D.1.; Liu, S.; Ge, Y.; Lan, Y.*; Chen, Y.* iScience. 2020, 23, 100755.

 

29. DNA-Encoded Library Chemistry: Amplification of Chemical Reaction Diversity for the Exploration of Chemical Space.  PDF

Huang, Y.; Savych, O.; Moroz, Y.; Chen, Y.*; Goodnow, R. A.* Aldrichimica Acta. 2019, 52, 3, 75-87. Invited Review.

 

28. Intermolecular Radical Addition to Ketoacids Enabled by Boron Activation.  PDF

Xie, S.; Li, D.; Huang, H.; Zhang, F.; Chen, Y.* J. Am. Chem. Soc. 2019, 141, 41, 16237-16242. Highlighted by Chinese Academy of Sciences.

 

27. Acyl Radical Smiles Rearrangement to Construct Hydroxybenzophenones by Photoredox Catalysis.  PDF

Li, J.; Liu, Z.; Wu, S.; Chen, Y.* Org. Lett. 2019, 21, 2077-2088.

 

26. Photocatalysis Enables Visible-Light Uncaging of Bioactive Molecules in Live Cells.  PDF

Wang, H; Li, W.; Zeng, K.; Wu, Y.; Zhang, Y.; Xu, T.*; Chen, Y.Angew. Chem., Int. Ed. 2019, 58, 561-565. Highlighted by Wiley China, Advanced Science News, and Chinese Academy of Sciences.

 

25. Visible Light-Driven Organic Photochemical Synthesis in China.  PDF

Chen, Y.*; Lu, L. Q.*; Yu, D. G.*; Zhu, C. J.*; Xiao, W. J.Sci. China Chem. 2019, 62, 24–57. Invited Review.

 

24. Cyclic Iodine Reagents Enable Allylic Alcohols for Alkyl Boronate Addition/Rearrangement by Photoredox Catalysis.  PDF

Liu, M; Huang, H.; Chen, Y.*  Chin. J. Chem. 2018, 36, 1209-1212. Special Issue for Prof. Xiyan Lu’s 90th Birthday.

 

23. Photochemistry of Hypervalent Iodine Compounds.  PDF

Jia, K.; Chen, Y.*  Patai’s Chemistry of Functional Groups. Marek, I, Olofsson, B., Rappoport, Z., Ed.; John Wiley & Sons, 2018.

 

22. Metal-Free C(sp3)-H Allylation via Aryl Carboxyl Radicals Enabled by Donor-Acceptor Complex.  PDF

Li, Y.1; Zhang, J.1; Li, D.; Chen, Y.*  Org. Lett. 2018, 20, 3296-3299.

 

21. Visible-Light-Induced Alkoxyl Radical Generation for Inert Chemical Bond Cleavage/Functionalizations.  PDF

Jia, K.; Chen, Y.*  Chem. Commun. 2018, 54, 6105-6112.  Invited Feature Article.

 

20. Investigations of Alkynyl Benziodoxole Derivatives for Radical Alkynylations in Photoredox Catalysis.  PDF

Pan, Y.; Jia, K.; Chen, Y.*; Chen, Y.*  Beilstein J. Org. Chem. 2018, 14, 1215-1221.  Invited Thematic Series “Hypervalent Iodine Chemistry in Organic Synthesis”.

 

19. Selective P-C(sp3) Bond Cleavage and Radical Alkynylation of α-Phosphorus Alcohols by Photoredox Catalysis.  PDF

Jia, K.; Li, J.; Chen, Y.*  Chem. Eur. J. 2018, 24, 3174–3177.

 

18. Donor-Acceptor Complex Enables Alkoxyl Radical Generation for Metal-Free C(sp3)-C(sp3) Cleavage and Allylation/Alkenylation.  PDF

Zhang, J.; Li, Y.; Xu, R.; Chen, Y.*  Angew. Chem., Int. Ed. 2017, 56, 12619 –12623. Highlighted by Science Foundation in China, China Science Daily, Chin. J. Org. Chem. and Chinese Academy of Sciences.

 

17. Selective Carbonyl-C(sp3) Bond Cleavage to Construct Ynamides, Ynoates, and Ynones by Photoredox Catalysis.  PDF

Jia, K.; Pan, Y.; Chen, Y.*  Angew. Chem., Int. Ed. 2017, 56, 2478 –2481. Highlighted by Chin. J. Org. Chem. and Chinese Academy of Sciences.

 

16. Visible-Light-Induced Carboxyl and Alkoxyl Radical Generations and Reactions.  PDF

Zhang, J.; Chen, Y.*  Acta Chim. Sin. 2017, 75, 41-48. Invited Review on “Organic Photochemistry” Special Issue.

 

15. Polarity-Reversed Allylations of Aldehydes, Ketones, and Imines Enabled by Hantzsch Ester in Photoredox Catalysis.  PDF

Qi, L.; Chen, Y.*  Angew. Chem., Int. Ed. 2016, 55, 13312-13315.

 

14. Radical Decarboxylative Functionalizations Enabled by Dual Photoredox Catalysis.  PDF

Huang, H.1; Jia, K.1; Chen, Y.*  ACS Catal. 2016, 6, 4983-4988. Invited Perspective.

 

13. Visible-Light-Induced Alkoxyl Radical Generation Enables Selective C(sp3)-C(sp3) Bond Cleavage and Functionalizations.  PDF

Jia, K.; Zhang, F.; Huang, H.; Chen, Y.* J. Am. Chem. Soc. 2016, 138, 1514-1517. Highlighted by Organic Chemistry Portal and Chinese Academy of Sciences.

 

12. Generation  of Alkoxyl Radicals by Photoredox Catalysis Enables Selective C(sp3)-H Functionalization under Mild Reaction Conditions.  PDF

Zhang, J.; Li, Y.; Zhang, F.; Hu, C.; Chen, Y.* Angew. Chem., Int. Ed. 2016, 55, 1872-1875. Highlighted by Angew. Chem., Int. Ed.

 

11. Chemoselective and Fast Decarboxylative Allylation by Photoredox Catalysis under Mild Conditions.  PDF

Hu, C.; Chen, Y.* Org. Chem. Front. 2015, 2, 1352-1355.

 

10. Dual Hypervalent Iodine(III) Reagents and Photoredox Catalysis Enable Decarboxylative Ynonylation under Mild Conditions.  PDF

Huang, H.1; Zhang, G.1; Chen, Y.* Angew. Chem., Int. Ed. 2015, 54, 7872-7876. Highlighted by Chin. J. Org. Chem. and Chinese Academy of Sciences.

 

9. Biomolecule-Compatible Chemical Bond-Formation and Bond-Cleavage Reactions Induced by Visible Light.  PDF

Hu, C.; Chen, Y.* Tetrahedron Lett. 2015, 56, 884-888. Invited Digest.

 

8. Hypervalent Iodine Reagents Enable Chemoselective Deboronative/Decarboxylative Alkenylation by Photoredox Catalysis.  PDF

Huang, H.; Jia, K.; Chen, Y.* Angew. Chem., Int. Ed. 2015, 54, 1881-1884. Highlighted by Synfacts.

 

7. Visible-Light-Induced Chemoselective Reductive Decarboxylative Alkynylation under Biomolecule-Compatible Conditions.  PDF

Yang, J.; Zhang, J.; Qi, L.; Hu, C.; Chen, Y.* Chem. Commun. 2015, 51, 5275-5278. 2015 Emerging Investigator Issue.

 

6. Visible-Light-Induced Chemoselective Deboronative Alkynylation under Biomolecule-Compatible Conditions.  PDF

Huang, H.; Zhang, G.; Gong, L.; Zhang, S.; Chen, Y.* J. Am. Chem. Soc. 2014, 136, 2280-2283. Highlighted by Chin. J. Org. Chem., Organic Chemistry Portal, and Synfacts.

 

 

5. Discovery and Biological Characterization of Geranylated RNA in Bacteria.  PDF

Dumelin, C.E.; Chen, Y.; Leconte, A.M.; Chen, Y.G.; Liu, D.R.* Nature Chem. Bio. 2012, 8, 913-919.

 

4. A Biomolecule-Compatible Visible-Light-Induced Azide Reduction from a DNA-Encoded Reaction-Discovery System.  PDF

Chen, Y.; Kamlet, A. S.; Steinman, J. B.; Liu, D. R.* Nature Chem. 2011, 3, 146-153.

 

3. Ruthenium-Catalyzed Three-Component Coupling via Hydrative Conjugate Addition of Alkynes to Alkenes: One-Pot Synthesis of 1,4-Dicarbonyl Compounds.  PDF

Chen, Y.; Park, S. H.; Lee, C. W.; Lee, C.*  Chem. Asian J. 2011, 6, 2000-2004.

 

2. Tris(acetylacetonato)iron(III).  PDF

Chen, Y.; Lee, C.* e-EROS Encyclopedia of Reagents for Organic Synthesis; Paquette, L. A., Ed.; John Wiley & Sons, 2007.

 

1. Ruthenium-Catalyzed Hydrative Cyclization of 1,5-Enynes. PDF

Chen, Y.; Ho, D. M.; Lee, C.*  J. Am. Chem. Soc. 2005, 127, 12184-12185.